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TRAB - ANTICORPO ANTI RECEPTOR DE TSH

Material:

Soro

Instruções de coleta:

Jejum de 8 horas. Anotar uso de medicamentos, em especial drogas anti-tireoideanas e hormônios tireoideanos. Enviar amostra congelada.

Informações:

Avaliação, diagnóstico e acompanhamento de doença de Graves. Os anticorpos anti-receptores de TSH são dirigidos contra epítopos do receptor de TSH. Existem duas classes de TRAB potencialmente associadas a distúrbios da tireóide: (a) anticorpos tireoestimuladores, causadores do hipertireoidismo de Graves, e (b) anticorpos bloqueadores, que impedem a ligação do TSH. Estes anticorpos podem ser encontrados sozinhos ou em conjunto em doença de Graves e em raros casos de tireoidite de Hashimoto. Sua determinação é útil na predição de recidivas após tratamento e também no diagnóstico de hipertireoidismo neonatal.

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